Química-Física Molecular - Maria Paula Matos Marques


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« VOLTAR	MARIA PAULA MATOS MARQUES
	Categoria profissional Professora Auxiliar da Faculdade de Ciências e Tecnologia da Universidade de Coimbra Endereço Departamento de Bioquímica Faculdade de Ciências e Tecnologia Universidade de Coimbra Apartado 3126 3001-401 Coimbra E-mail pmc@ci.uc.pt Telefone +351 239826541 URL https://woc.uc.pt/bioquimica/person/ppgeral.do?idpessoa=18 Publicações Antioxidant Phenolic Esters with Potential Anticancer Activity: A Raman Spectroscopy Study R. Calheiros, N.F.L. Machado, S.M. Fiuza, A. Gaspar, J. Garrido, N. Milhazes, F. Borges, M.P.M. Marques Journal of Raman Spectroscopy 39, 95-107 (2008) Effect of the Metal Center on the Antitumor Activity of the Analogous Dinuclear Spermine Chelates (PdCl2)(2)(Spermine) and (PtCl2)(2)(Spermine) A.S. Soares, S. Fiuza, M.J. Goncalves,L.A.E. Batista de Carvalho, M.P.M. Marques , A.M. Urbano Letters in Drug Design & Discovery 4, 460-463 (2007) Cyclodextrin Encapsulation of Biomimetic Organometallic Cancer Drug Candidates S.S. Braga, F A.A. Paz, V. Mokal, M. Pillinger, M.P.M. Marques, C.C. Romao, I.S. Goncalves Drugs of the Future 32, 101 (2007) Spectroscopic and Electrochemical Studies of Cocaine-Opioid Interactions J. Garrido, M.P.M. Marques, A.M.S. Silva, T.R.A. Macedo, A.M. Oliveira-Brett, F. Borges Analytical and Bioanalytical Chemistry 388, 1799-1808 (2007) Vibrational Spectroscopy Studies on Biologically Relevant Molecules. From Anticancer Agents to Drugs of Abuse M.P.M. Marques, F. Borges, A.M. Amorim da Costa, L.A.E. Batista de Carvalho K. Kneip, R. Aroca, H. Kneipp, E. Wentrup-Byrne (Eds.), In "New Approaches in Biomedical Spectroscopy" , ACS Symposium, série 963, cap.21 (2007) Electrochemical and Spectroscopic Characterisation of Amphetamine-Like Drugs: Application to the Screening of 3,4-Methylenedioxymethamphetamine (MDMA) and its Synthetic Precursors N. Milhazes, P. Martins, E. Uriarte, J. Garrido, R. Calheiros, M.P.M. Marques, F. Borges Analytica Chimica Acta 596, 231-241 (2007) Phenolic Esters with Potential Anticancer Activity - The Structural Variable N.F.L. Machado, R. Calheiros, S.M. Fiuza, F. Borges, A. Gaspar, J. Garrido, M.P.M Marques Journal of Molecular Modeling 13, 865-877 (2007) Evidence of a Local Order in Concentrated Aqueous Solutions of Salts Constituted by ions of Different Valences. X-ray Diffraction and Raman Spectroscopy Experiments M.A. Marques, M.I.D. Marques, M.I. Cabaco, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa Journal of Molecular Liquids 134, 142-150 (2007) Vibrational Spectroscopy Studies on Linear Polyamines M.P.M. Marques, L.A.E. Batista de Carvalho Biochemical Society Transactions 35, 374-380 (2007) Transverse Acoustic Modes of Biogenic and α,ω-polyamines: A Study by Inelastic Neutron Scattering and Raman Spectroscopies Coupled to DFT Calculations L.A.E. Batista de Carvalho, M.P.M. Marques, J. Tomkinson Journal of Physical Chemistry A 110, 12947-12954 (2006) New Insights on the Anticancer Properties of Dietary Polyphenols P. Fresco, F. Borges, C. Diniz, M.P.M. Marques Medicinal Research Reviews 26, 747-766 (2006) Cytotoxic and COX-2 Inhibition Properties of Hydroxycinnamic Derivatives M.P.M. Marques, F. Borges, J. Sousa, R. Calheiros, J. Garrido, A. Gaspar, F. Antunes, C. Diniz, P. Fresco Letters in Drugs Design & Discovery 3, 316-320 (2006) Drug-Excipient Interactions in Ketoprofen: A Vibrational Spectroscopy Study L.A.E. Batista de Carvalho, M.P.M. Marques, J. Tomkinson Biopolymers 82, 420-424 (2006) Structural Characterization of Agmatine at Physiological Condition A. Toninello, V. Battaglia, M. Salvi, R. Calheiros, M.P.M. Marques Structural Chemistry 17, 163-175 (2006) Pt(II) vs Pd(II) Polyamine Complexes as New Anticancer Drugs: A Structure-Activity Study S.M. Fiuza, A.M. Amado, L.A.E. Batista de Carvalho, P.J. Oliveira, V.A. Sardão, M.P.M Marques Letters in Drug Design & Discovery 3, 149-151 (2006) Agmatine is Transported in Liver Mitochondria by a Specific Electrophoretic Mechanism M. Salvi, V. Battaglia, M. Mancon, S. Colombatto, R. Calheiros, M.P.M. Marques, M.A. Grillo, A. Toninello Biochemical Journal 396, 337-345 (2006) β-Nitrostyrene Derivatives as Potential Antibacterial Agents: A Structure-Property-Activity Relationship Study N. Milhazes, R. Calheiros, M.P.M. Marques, J. Garrido, M.N.D.S. Cordeiro, C. Rodrigues, S. Quinteira, C. Novais, L. Peixe, F. Borges Bioorganic & Medicinal Chemistry 14, 4078-4088 (2006) Conformational Analysis of the Potential Anticancer Agent Ethyl Trihydroxycinnamate – A Combined Raman Spectroscopy and Ab Initio Study J.B. Sousa, R. Calheiros, V. Rio, F. Borges, M.P.M. Marques Journal of Molecular Structure 783, 122-135 (2006) Structure-Property Studies on the Antioxidant Activity of Flavonoids Present in Diet S. Teixeira, C. Siquet, C. Alves, I. Boal, M.P.M. Marques, F. Borges, J.L.F.C. Lima, S. Reis Free Radical Biology Medicine 39, 1099-1108 (2005) Raman Spectroscopy as a Screening Method for Drugs of Abuse and Their Precursors M.P.M. Marques, R. Calheiros, N. Milhazes, F. Borges Clinica Chimica Acta 355, S316-316 (2005) New Insights on Cocaine-Opiates Interactions M.P.M. Marques, J.M.P.J. Garrido, A.M.S. Silva, F. Borges, A.M.O. Brett Clinica Chimica Acta 355, S316-317 (2005) X-Ray Diffraction Investigations of the Existence of a Local Order in Concentrated Aqueous Solutions of Salts Constituted by Ions of Different Valences M.I. Cabaço, A.M. Gaspar, M.I. de Barros Marques, M. Alves Marques, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa Conference of the European Molecular Liquids Group, Praga, República Checa, (2005) The Structure of Concentrated Aqueous Solutions of Nitrates of Metallic Cations M. Alves Marques, M.I. Cabaço, M.I. Barrosa Marques, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa In Proccedings VIth Liquid Matter Conference, Utrech, Holanda, (2005) Raman Spectroscopy and X-Ray Diffraction Investigations on Concentrated Aqueous Solutions of Metallic Cations M.I. Cabaço, M. Alves Marques, M.I. Barrosa Marques, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa In Proceedings Thermodynamics 2005 Meeting, Sesimbra, Portugal, (2005) Local Order in Concentrated Aqueous Solutions of Inorganic Salts Constituted by Ions of Different Valences M. Alves Marques, M.I. Barrosa Marques, M.I. Cabaço, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa 4tyh IUPAC Congress, Beijing, China, 14-19 (2005) Theoretical Studies on Solid α,ω-Diamine Salts A.M. Amado, S.M. Fiuza, J.C. Otero, M.P.M. Marques, L.A.E. Batista de Carvalho Lecture Series on Computer and Computational Sciences 4, 21-24 (2005) Performance of Different DFT/ECP Combinations in the Study of Platinum Anticancer Drugs S. Fiúza, A.M. Amado, J.C. Otero, M.P.M. Marques, L.A.E. Batista de Carvalho Lecture Series on Computer and Computational Sciences 4, 191-194 (2005) Inclusion of Molybdenocene Dichloride (Cp₂MoCl₂) in 2-Hydroxypropyl- and Trimethyl-β-cyclodextrin: Structural and Biological Properties S.S. Braga, J.B. Sousa, M.P.M. Marques, M. Pillinger, J.J. C. Teixeira-Dias, I.S. Gonçalves Journal of Organometallic Chemistry 690 , 2905-2912 (2005) Spectroscopic and Theoretical Studies on Solid 1,2-Ethylenediamine Dihydrochloride Salt A.M. Amado, J.C. Otero, M.P.M. Marques, L.A.E. Batista de Carvalho ChemPhysChem 5, 1837-1847 (2004) Identification of Synthetic Precursors of Amphetamine-like Drugs based on Raman Spectroscopy and ab Initio Calculations: β-Methyl-β-nitrostyrene Derivatives N. Milhazes, F. Borges, R. Calheiros, M.P.M. Marques The Analyst 129, 1106-1117 (2004) Phenolic Acid Derivatives with Potential Anticancer Properties – A Structure-Activity Relationship Study. Part 1: Methyl, Propyl and Octyl Esters of Caffeic and Gallic Acids S.M. Fiuza, C.A. Gomes, L.J. Teixeira, T. Girão da Cruz, M.N. Cordeiro, N. Milhazes, F. Borges, M.P.M. Marques Bioorganic & Medicinal Chemistry 12, 3581-3589 (2004) Intra- versus Interchain Interactions in α,ω-Polyamines: A Raman Spectroscopy Study A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de carvalho Vibrational Spectroscopy 35, 165-171 (2004) Cytotoxic Activity of Metal Complexes of Biogenic Polyamines: Polynuclear Platinum(II) Chelates L.J. Teixeira, M. Seabra, E. Reis, M.T. Girão da Cruz, M.C. Pedroso de Lima, E. Pereira, M.A. Miranda, M.P.M. Marques Journal of Medicinal Chemistry 47, 2917-2925 (2004) Conformational Analysis of a Trihydroxylated Derivative of Cinnamic Acid – A Combined Raman Spectroscopy and Ab Initio Study S.M. Fiuza, E. Van Besien, N. Milhazes, F. Borges, M.P.M. Marques Journal of Molecular Structure 693, 103-118 (2004) β-Nitrostyrene Derivatives - A Conformational Study by Combined Raman Spectroscopy and Ab Initio MO Calculations R. Calheiros, N. Milhazes, F. Borges, M.P.M. Marques Journal of Molecular Structure 692, 91-106 (2004) Conformational Study of Pt(II) Complexes with Polyamines as Possible New Anticancer Agents M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson The Rutherford Appleton Laboratory, ISIS Facility Annual Report (2002-2003) Anticancer Activity of Phenolic Acids of Natural or Synthetic Origin: A Structure-Activity Study C.A. Gomes, T. Girão da Cruz, J.L. Andrade, N. Milhazes, F. Borges, M.P.M.Marques Journal of Medicinal Chemistry 46,5395-5401 (2003) Ab Initio Conformational Study of Caffeic Acid E. Van Besien, M.P.M. Marques Journal of Molecular Structure (THEOCHEM) 625, 265-275 (2003) Raman Spectra of Putrescine, Spermidine and Spermine Polyamines and Their N-Deuterated and N-Ionised Derivatives A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de Carvalho Journal of Raman Spectroscopy 34, 357-366 (2003) Conformational Studies on Biogenic Polyamines M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson The Rutherford Appleton Laboratory, ISIS Facility Annual Report (2001-2002) New Anticancer Agents: Structure-Activity Relationships M.P.M. Marques, F. Borges, E. Pereira, N. Milhazes, T. Girão, L.J. Teixeira, C. A. Gomes Drugs of the Future 27 (Suppl. A) 141 (2002) Study of Carvedilol by Combined Raman Spectroscopy and Ab Initio MO Calculations M.P.M. Marques, P.J. Oliveira, A.J.M. Moreno, L.A.E. Batista de Carvalho Journal of Raman Spectroscopy 33 (10), 778-783 (2002) Experimental and Theoretical Evidence of CH···O Hydrogen Bonding in Liquid 4-Fluorobenzaldehyde P.J.A. Ribeiro-Claro, M.P.M. Marques, A.M. Amado ChemPhysChem 3, 599-606 (2002) The Carbon-Hydrogen Stretching Region of the Raman Spectra of 1,6-Hexane-diamine: N-Deuteration, Ionization and Temperature Effects A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de Carvalho Vibrational Spectroscopy 29, 61-67 (2002) Study of Biogenic and α,ω-Polyamines by Combined Inelastic Neutron Scattering and Raman Spectroscopies, and Ab Initio MO Calculations M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson The Journal of Physical Chemistry A 106, 2473-2482 (2002) Cytotoxic Effects of Metal Complexes of Biogenic Polyamines. I – Platinum(II) Spermidine Compounds: Prediction of their Antitumour Activity M.P.M. Marques, T. Girão, M.C. Pedroso de Lima, A. Gameiro, E. Pereira, P. Garcia Biochimica et Biophysica Acta - Molecular Cell Research 1589 (1), 63-70 (2002) Evidence of CH···O Hydrogen Bonds in Liquid 4-Ethoxybenzaldehyde by NMR and Vibrational Spectroscopies M.P.M. Marques, A.M. Amorim da Costa, P.J.A. Ribeiro-Claro The Journal of Physical Chemistry A 105, 5292-5297 (2001) Raman Spectra of Putrescine, Spermidine and Spermine Polyamines and Their N-Deuterated and N-Ionised Derivatives A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de Carvalho J. Mink, G. Jalsovszky e G. Keresztury (Eds.). XVIII International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 735 (2002) Conformational Analysis of the Protonated Amines [H₃N(CH₂)_nNH₃]²⁺ (n=7 to 10, n=12), Spermidine and Spermine L.A.E. Batista de Carvalho, M.P.M. Marques, J. Tomkinson J. Mink, G. Jalsovszky e G. Keresztury (Eds.). XVIII International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 597 (2002) Effects of Carvedilol on Isolated Heart Mitochondria: Evidences for a Protonophoretic Mechanism P.J. Oliveira, M.P.M. Marques, L.A.E. Batista de Carvalho, A.J.M. Moreno Biochemical and Biophysical Research Communications 276, 82-87 (2000) Conformational Studies on Biogenic Polyamines M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson The Rutherford Appleton Laboratory, ISIS Facility Annual Report (1999-2000) Theoretical Approach to the Conformational Preferences of Putrescine M.P.M. Marques, L.A.E. Batista de Carvalho D.M.L. Morgan, A. White, F. Sánchez-Jiménez and S. Bardocz (Eds.). COST 917: Biogenically Active Amines in Food. European Commission, Luxembourg, vol. IV, 122-129 (2000) Study of Copper(II) Polyazamacrocylic Complexes by Electronic Absorption Spectrophotometry and EPR Spectroscopy C.F.G.C. Geraldes, M.P.M. Marques, Baltazar de Castro, E. Pereira European Journal of Inorganic Chemistry 2000, 559-565 (2000) Conformational Analysis of the Protonated Diamines [H₃N(CH₂)_nNH₃]²⁺ (n=2 to 6) L.A.E. Batista de Carvalho, M.P.M. Marques S.-L. Zhang e B.-F. Zhu (Eds.). XVII International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 822 (2000) Structural Studies on Biogenic Polyamines by Combined Raman and INS Spectroscopies and Ab Initio Methods M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson S.-L. Zhang e B.-F. Zhu (Eds.). XVII International Conference on Raman Spectroscopy, John Wiley & Sons Ltd, Chichester, 818 (2000) Oxygen-by-Sulphur Substitutions in Glycine: Conformational and Vibrational Effects L.A.E. Batista de Carvalho, M.P.M. Marques, J.J.C. Teixeira-Dias Journal of the Chemical Society-Perkin Transactions 2, 2507-2514 (1999) Conformational Study of 1,2-Diaminoethane by Combined Ab Initio MO Calculations and Raman Spectroscopy L.A.E. Batista de Carvalho, L.E. Lourenço, M.P.M. Marques Journal of Molecular Structure 482, 639-646 (1999) Structural Study of Putrescine by Combined Raman Spectroscopy and Ab Initio Methods M.P.M. Marques, L.A.E. Batista de Carvalho J. Greve, G.J. Puppels e C. Otto (Eds.), In Spectroscopy of Biological Molecules: New Directions, Kluwer Academic Publishers, Dordrecht, Holanda, 431 (1999) Conformational Analysis and Vibrational Frequencies of Alanine and Its Sulphur Tautomers L.A.E. Batista de Carvalho, M.P.M. Marques, J.J.C. Teixeira-Dias J. Greve, G.J. Puppels e C. Otto (Eds.), In Spectroscopy of Biological Molecules: New Directions, Kluwer Academic Publishers, Dordrecht, Holanda, 77 (1999) Conformational Analysis of Biologically Relevant Diamines by Raman Spectroscopy and Ab Initio MO Calculations L.A.E. Batista de Carvalho, M.P.M. Marques A.M. Heyns (Ed.). XVI International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 232 (1998) NMR Conformational Study of Diamagnetic Complexes of Some Triazatriacetate Macrocycles Carlos F.G.C. Geraldes, M.P. M. Marques, A.D. Sherry Inorganica Chimica Acta 273 288-298 (1998) Conformational and Coordination Equilibria on DOTA Complexes of Lanthanide Metal Ions in Aqueous Solution Studied by ¹H-NMR Spectroscopy S. Aime, M. Botta, M. Fasano, M.P.M. Marques, C.F.G.C. Geraldes, D. Pubanz, A.E. Merbach Inorganic Chemistry 36, 2059-2068 (1997) Conformational Analysis of Glycine and its Sulphur Tautomers by Ab Initio MO Methods L.A.E. Batista de Carvalho, M.P.M. Marques, J.J.C. Teixeira-Dias P. Carmona, R. Navarro, A. Hernanz (Eds.), Spectroscopy of Biological Molecules: Modern Trends, Kluwer Academic Publishers, Dordrecht, Holanda, 547 (1997) Conformational Analysis of Piperazine by Vibrational Spectroscopy and Ab Initio Calculations M.P.M. Marques, L.A.E. Batista de Carvalho P. Carmona, R. Navarro, A. Hernanz (Eds.), Spectroscopy of Biological Molecules: Modern Trends, Kluwer Academic Publishers, Dordrecht, Holanda, 549 (1997) Ab initio SCF MO Calculations on Triaza and Tetraaza Cyclic Amines P.J.A. Ribeiro-Claro, A.M. Amado, M.P.M. Marques, J.J.C. Teixeira-Dias Journal of the Chemical Society – Perkin Transactions 2, 1161-1167 (1996) NMR Conformational Study of the Lanthanide(III) Complexes of DOTA in Aqueous Solution M.P.M Marques, C.F.G.C. Geraldes, A.D. Sherry, A.E. Merbach, H. Powell, D. Pubanz, S. Aime, M. Botta Journal of Alloys and compounds 225, 303-307 (1995) Formation and Decomposition Study of Electrochemically generated Ni(III)NOTA Complexes in Aqueous Solution Baltazar de Castro, J. Gomes, M.P.M Marques, C.F.G.C. Geraldes Journal of the Chemical Society, Dalton Transactions, 2041-2044 (1995) Study of the Kinetics of the Formation of the EuDOTA^- Complex M.P.M. Marques, W. D'Olieslager, C.F.G.C. Geraldes European Journal of Solid State and Inorganic Chemistry 28, 251 (1991) The Protonation Sequence of Some Triaza Macrocycles Studied by Potentiometry and NMR Spectroscopy C.F.G.C. Geraldes, A.D. Sherry, M.P.M. Marques, M.C. Alpoim, S. Cortes Journal of the Chemical Society-Perkin Transactions II, 137-146 (1991) The Study of Lanthanide-NOTA Chelates as Aqueous Paramagnetic Probes in Structural Nuclear Magnetic Resonance Spectroscopy C.F.G.C. Geraldes, M.P.M. Marques, A.D. Sherry Ciência Biológica 12, 82 (1987) A NMR Study of Lanthanide-NOTA Chelates as Aqueous Paramagnetic Shift and Relaxation Probes C.F.G.C. Geraldes, M.P.M. Marques, A.D. Sherry Inorganica Chimica Acta 139, 311-313 (1987) A NMR Study of Ln(NOTA) Chelates as Axially Symmetric Aqueous Shift Reagents C.F.G.C. Geraldes, M.C. Alpoim, M.P.M. Marques, A.D. Sherry, M. Singh Revista Portuguesa de Química 27, 346 (1985) Nuclear Magnetic Resonance and Potentiometric Studies of the Protonation Scheme of a Triaza Triacetic Macrocycle and its Complexes with Lanthanum and Lutetium C.F.G.C. Geraldes, M.C. Alpoim, M.P.M. Marques, A.D. Sherry, M. Singh Inorganic Chemistry 24, 3876-3881 (1985) Projectos Novas Abordagens Terapêuticas no Cancro: Desenho Racional e Síntese de Novos Ligandos dos Receptores A3 da Adenosina (PTDC/QUI/70359/2006) Hibridização Molecular no Desenvolvimento de Novas Drogas Anticancerígenas (CAPES/CPLP-4.1.3.) Síntese de Metabolitos de Drogas de Abuso (Opiáceos). Avaliação das Interacções entre os Metabolitos dos Opiáceos e a Cocaína” (Fundação Ilídio Pinho, Portugal, 2006) Health Implications of Dietary Amines (Acção COST 922 - WG 2) Aplicação de um Novo Método Natural na Prevenção do Abrolhamento e Monitorização em Tempo Real da Maturação de Alimentos de Origem Vegetal” (AGRO 8.1/691) Desenvolvimento de Novos Agentes Anticancerígenos: Derivados Fenólicos de Origem Natural ou Sintética – Relações Estrutura-Actividade (POCI/QUI/55631/2004) Estudo Bioquímico e Comportamental das Interacções Opiácios – Cocaína (POCI/SAU-FCF/58330/2004) Complexos de Pt(II) com Poliaminas Biogénicas como Novos Agentes Anticancerígenos: Relações Estrutura-Actividade (POCTI/QUI/47256/2002) Estudo de Poliaminas Biogénicas e de seus Complexos Metálicos (POCTI/QUI/33199/2000) Ligações de Hidrogénio C-H^...O em Líquidos (POCTI/35408/QUI/00) Análise Conformacional de Poliaminas: Estudo por Espectroscopia Vibracional e Cálculos Ab Initio (PBIC/C/QUI/2219/95)

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MARIA PAULA MATOS MARQUES